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Objective To evaluate the effect of direct-vision and two stiches method and other techno logical improvements on PPH surgical operation by prospective randomized controlled study.Methods A total of 683 patients were randomly assigned.Direct-vision and two stiches method technological improvements were applied in observation group,while standard operation procedures were performed in control group.Operation time,blood loss during operation,specimen size,post-operative complication and other conditions were compared between observation group and control group.Results In 350 cases of the observation group,the average surgical time was (12.2 ± 4.0)minutes,blood loss during operation (4.95 ± 2.82)mL and specimens width (2.61 ± 0.32)cm.2 patients with hemorrhage were performed hemostasis after surgery.5 cases suffered from edema or thrombus in haemorrhoids zones after surgery.In 333 cases of the control group,the average surgical time was (17.2 ± 3.6)minutes,blood loss during operation (7.55 ± 3.94) mL and specimens width (1.18 ± 0.56) cm.5 patients were performed hemostasis after surgery,14 cases suffering from edema or thrombus in haemorrhoids zones after surgery,postoperative infection in 1 case,rectostenosis in 1 case,and 1 case in rectovaginal fistula.In the observation group,operation time was shorter than that in the control group.No significance was found in excision width and depth.The serious complications after surgery are fewer in observation group than that in the control group.Conclusion The direct-vision and two stiches method and other technological improvements are safe and effective,meanwhile operation difficulty can be reduced.
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Objective:To study the relationship between plasma homocysteine (Hcy),serum folate,Vitamin B12 levels and Vascular dementia (VD).Methods:30 VD patients,58 patients with nondemented cerebral infarction and 30 normal subjects of the same age were recruited in to the study.Their plasma Hcy levels were measured by reversed phase high performance liquid chromatography (RP-HPLC),and the levels of serum folate and Vitamin B12 were also determined by radioimmune assay (RIA).Results:Mean of Plasma homocysteine concentrations were significantly higher in VD group than in the nondemented cerebral infarction group.Which were significantly higher in the nondemented cerebral infarction group than in the normal subjects of the same age.Serum folate levels in the VD group were significantly lower than those in the nondemented cerebral infarction group.Which were significantly lower than those of normal subjects.Conclusion:Hcy may be a new risk factor for the onset of VD.
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<p><b>OBJECTIVE</b>To explore the changes of soluble interleukin-2 receptor(sIL-2R) in serum and cerebrospinal fluid (CSF) of patients with delayed encephalopathy after acute carbon monoxide poisoning (DEACMP).</p><p><b>METHODS</b>There were 31 patients with DEACMP, 32 patients with other encephalopathy and 31 controls in this study. The levels of sIL-2R in serum and CSF were detected by ELISA.</p><p><b>RESULTS</b>Serum sIL-2R in patients with DEACMP[(329.21 +/- 160.99)U/ml] was significantly higher than that in control[(115.67 +/- 89.58) U/ml, P < 0.05)], but not significantly different from that in the other encephalopathy group[(367.50 +/- 123.14) U/ml, P > 0.05)]. CSF sIL-2R in patients with DEACMP[(54.48 +/- 43.04) U/ml] measured a little before discharge was significantly lower than that in patients with the other encephalopathy[(110.24 +/- 76.56) U/ml, P < 0.05)], but not significantly different from that in the control group[(34.96 +/- 22.70)U/ml, P > 0.05)]. At the pre-discharged period, CSF sIL-2R in patients with DEACMP[(100.26 +/- 93.65) U/ml] was significantly higher than that at the early stage of hospitalization[(52.28 +/- 43.31) U/ml, P < 0.05)]. No significant difference in serum sIL-2R was found between early stage of hospitalization[(338.34 +/- 161.53) U/ml] and pre-discharge [(351.31 +/- 175.93) U/ml, P > 0.05)].</p><p><b>CONCLUSION</b>The occurrence of DEACMP may be related with immunopathological damage. The sIL-2R levels in serum and CSF may give information about the state of immunological function of the patients with DEACMP and may contribute to determining the patient's condition and prognosis.</p>
Subject(s)
Humans , Brain Diseases , Cerebrospinal Fluid , Allergy and Immunology , Carbon Monoxide Poisoning , Cerebrospinal Fluid , Allergy and Immunology , Enzyme-Linked Immunosorbent Assay , Hospitalization , Receptors, Interleukin-2 , BloodABSTRACT
To distinguish the degrees of frostbite in early stage after freezing-thawing injuries is a most impor- tant yet difficult task. In order to seek the indicators of severity of injuries, we observed the relationship between the degrees of cold injuries and serum creatine phosphokinase (SCPK) levels. Results showed that after freezing the rabbit paws to 0℃, SCPK level began to rise. Freezing in the range of 0℃ to-25℃, SCPK levels rose inversely with the lowering of tissue temperature. The elevation of SCPK activity usually appeared 1 hr after freezing, reaching thepeak at 12 hours, and it began decline at 24 hours,returning to normal level at 72 hours after freezing.
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Rats were divided into 4 groups. Among them the control group was fed to the synthetic diet consisted of egg white powder, sucrose, plant oil, vitamins and salts mixture, the other 3 groups being fed to the same diet except that instead of egg white and sucrose in 20 % composition of diet liver, cabbage and yeast were used respectively.After the irradiation of 630 r, the 30 days mortality in control group was significantly higher than any other experimental group. As compared with the control group, the liver-fed group had longer survival time and more increment of body weight in the recovery period. It suggested that certain factors might exist in liver, cabbage or yeast for the protective effect on acute radiation damage though the action of known nutrients (especially essential trace elements) was not completely exclusive.